Publications

2015 Mitochondrial dysfunction in oocytes of obese mothers: transmission to offspring and reversal by pharmacological endoplasmic reticulum stress inhibitors


2015 Diabetes drug may help obese women conceive and have healthier children


2014 The small-molecule BGP-15 protects against heart failure and atrial fibrillation in mice


2014 Activating HSP72 in rodent skeletal muscle increases mitochondrial number and oxidative capacity and decreases insulin resistance


2014 Improvement of Insulin Sensitivity by a Novel Drug Candidate, BGP-15, in Different Animal Studies


2013 Synergetic Insulin Sensitizing Effect of Rimonabant and BGP-15 in Zucker-Obes Rats


2013 Hydroximic Acid Derivatives: Pleiotrophic Hsp Co-Inducers Restoring Homeostasis and Robustness


2012 BGP-15, a PARP-inhibitor, prevents imatinib-induced cardiotoxicity by activating Akt and suppressing JNK and p38 MAP kinases


2012 The HSP co-inducer BGP-15 can prevent the metabolic side effects of the atypical antipsychotics


2012 Novel Insulin Sensitizer Drug Candidate-BGP-15-Can Prevent Metabolic Side Effects of Atypical Antipsychotics


2012 Hsp72 preserves muscle function and slows progression of severe muscular dystrophy


2011 Effects of different small HSPB members on contractile dysfunction and structural changes in a Drosophila melanogaster model for Atrial Fibrillation


2011 Membrane-Lipid Therapy in Operation: The HSP Co-Inducer BGP-15 Activates Stress Signal Transduction Pathways by Remodeling Plasma Membrane Rafts


2010 BGP-15 inhibits caspase-independent programmed cell death in acetaminophen-induced liver injury


2010 Beneficial effect of the insulin sensitizer (HSP inducer) BGP-15 on olanzapine induced metabolic disorders


2009 Small-molecule modulation of cellular chaperones to treat protein misfolding disorders.


2009 Improvement of insulin sensitivity by a novel drug, BGP-15, in insulin-resistant patients. A proof of concept randomized double-blindclinicaltrial


2008 HSP72 protects against obesity-induced insulin resistance


2007 Can The Stress Protein Response be Controlled by 'membrane-lipid Therapy'?


2006 BGP-15, a new insulin sensitizer targeting mitochondria


2006 BGP-15, a new type insulin sensitizer is protective in rat experimental periodontitis


2006 BGP-15, a new type of insulin sensitizer


2006 Influence of BGP-15, a nicotinic amidoxime derivative, on the vascularization and growth of Murine hepatoma xenografts


2003 BGP-15, a hydroximic acid derivative, protects against cisplatin or taxol-induced peripheral neuropathy in rats


2002 Protecting Effect of PARP Inhibition on Ultraviolet Light-Induced Skin Damage


2002 Chemoprotective effect of a novel PARP inhibitor


2002 Reduction of acute photodamage in skin by topical application of a novel PARP inhibitor.


2002 BGP-15 - a novel poly(ADP-ribose) polymerase inhibitor - protects against nephrotoxicity of cisplatin without compromising its antitumor activity


2001 Mode of action observations of a new chemoprotective agent BGP-15


2001 Effect of poly(ADP-ribose) polymerase inhibitors on the ischemia-reperfusion-induced oxidative cell damage and mitochondrial metabolism in Langendorff heart perfusion system


2000 Protective effect of poly (ADP-ribose) polymerase inhibitors against cell damage induced by antiviral and anticancer drugs


2000 BGP-15, a nicotinic amidoxime derivate protecting heart from ischemia reperfusion injury through modulation of poly(ADP-ribose) polymerase