Science & Technology

About the Technology

Core technology of N-Gene is based on compounds in the family of hydroxylamine derivatives proven to restore, via modulating stress response, disturbed signaling pathways thereby treating the root cause of a wide range of disorders.

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Preclinical Developments

BGP-15 has been extensively investigated in preclinical models of diseases commonly related to targeted mechanisms of the compound.

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Clinical developments

N-Gene has completed three POC/POE human clinical trials in insulin resistance related therapeutic indications.

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Orphan Designation

An international group of scientists, led by Prof Gordon Lynch at the University of Melbourne, Australia, have shown that increasing the amount of HSP72 can have a beneficial effect in a mouse model of Duchenne muscular dystrophy.

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Intellectual Property

BGP-15 is eligible for Data Exclusivity protection for 5 years in the US and up to 10 years in the EU, in the diabetes indication, and has been awarded orphan status in Duchenne Muscular Dystrophy.

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