About the Technology

Core technology of N-Gene is based on compounds in the family of hydroxylamine derivatives proven to restore, via modulating stress response, disturbed signaling pathways thereby treating the root cause of a wide range of disorders. This complex effect comprises of membrane-specific lipid- interactions, lipid raft remodeling and restored expression of heat shock proteins (primarily HSP70 - 72), altogether improving organelle quality and reestablishing cell homeostasis.

Lead compound of the Company, BGP-15 has reached clinical stage and has been tested in phase 2 studies for mechanism (insulin sensitizing) and for assessment of efficacy in two therapeutic indications – protection against side effect of anti-psychotics, and treatment of T2DM – with promising results.